Neurotransmitter Review
نویسنده
چکیده
Ligand-Gated Channel Receptors. When a neurotransmitter molecule binds to a receptor that acts as a ligand-gated ion channel, a channel opens, allowing ions to flow across the membrane (see figure). The flow of positively charged ions into the cell depolarizes the portion of the membrane nearest the channel. Because this situation is favorable to the subsequent generation of an action potential, ligandgated channel receptors that are permeable to positive ions are called excitatory. Other ligand-gated channels are permeable to negatively charged ions. An increase of negative charge within the cell makes it more difficult to excite the cell and induce an action potential. Such channels accordingly are called inhibitory.
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